The Adventure of the Deranged Detective Sherlock Holmes in the 22nd Century : Season 1 Episode 6

Holmes fakes madness and babbles about oysters apparently after exposure to a boobytrapped puzzlebox, not infected with mind-altering nanobots. At Midgard Hospital are the suspected nanatech thieves: Dr. Cushing, Dr. Cuthbertson Smith and Dr. Chang. Smith is given away by the surgeons' knot on his retro nonvelcro shoes.